Recent Publications
We are pleased to present recent publications from our doctors at the Valley Heart and Vascular Institute.
2025
Frontiers in Digital Health
Evaluating diversity and stereotypes amongst AI generated representations of healthcare providers, 7
Anjali, A. [Anjali], Gupta, G., Agrawal, A. [Agrawal], & Gupta, H. (2025)
Circulation: Cardiovascular Imaging
AI-quantitative ct coronary plaque features associate with a higher relative risk in women: CONFIRM2-registry
Feuchtner, G.M., Lacaita, P.G., Bax, J.J., Rodriguez, F., Nakanishi, R., Pontone, G., Mushtaq, S., Buechel, R.R., Gräni, C., Patel, A.R., Singulane, C.C., Choi, A.D., Al-Mallah, M., Andreini, D., Karlsberg, R.P., Cho, G.W., Rochitte, C.E., Alasnag, M., Hamdan, A., … van Rosendael, A. (2025)
The Palgrave Encyclopedia of Disability
Disability After Cardiac Surgery
Jabagi, H., Schalm, E.E., Sun, L.Y. (2025).
Heart Rhythm O2
Correlation between mobile and 12-lead ECG among patients loading with intravenous sotalol: A PEAKS substudy
Steinberg, B.A., Mittal, S., Holubkov, R., Groh, C.A., Kennedy, R., Pokharel, P., Perez, M., Savona, S.J., Verma, N., Watt, K., Piccini, J.P., Bunch, T.J., & Deering, T.F. (2025).
Society for Cardiovascular Angiography & Interventions
Short-Term Mechanical Circulatory Support for Cardiogenice Shock
Tayal, R., & Grewal, J. (2024).
2024
Circulation: Arrythmia and Electrophysiology
Inappropriate Therapy and Shock Rates Between the Subcutaneous and Transvenous Implantable Cardiac Defibrillator: A Secondary Analysis of the PRAETORIAN Trial
Olde Nordkamp, L.R.A., Pepplinkhuizen, S., Ghani, A., Boersma, L.V.A., Kuschyk, J., El-Chami, M.F., Behr, E.R., Brouwer, T.F., Kaab, S., Mittal, S., Quast, A.B.E., van der Stuijt, W., Smeding, L., de Veld, J.A., Tijssen, J.G.P., Bijsterveld, N.R., Richter, S., Brouwer, M.A., de Groot, J.R., … PRAETORIAN Investigators (2024).
Heart Rhythm O2
Use of Continuous Cardiac Monitoring to Assess the Influence of Atrial Fibrillation Burden and Patterns on Patient Symptoms and Healthcare Utilization: The DEFINE AFib Study
Lakkireddy, D.R., Russo, A.M., Hylek, E.M., Mittal, S., Peacock, J., Hills, M.T., Stanelle, E.J., Lande, J.D., Franco, N.C., Johnson, L.C., Kanwar, R., Passman, R.S., & Piccini, J.P. (2024).
JACC: Cardiovascular Interventions
Conduction Disturbances After Transcatheter Aortic Valve Replacement: An Update on Epidemiology, Preventive Strategies, and Management
Nuche, J., Ellenbogen, K.A., Mittal, S., Windecker, S., Benavent, C., Philippon, F., & Rodés-Cabau, J. (2024)
Circulation: Arrhythmia and Electrophysiology
Using atrial fibrillation burden trends and machine learning to predict near-term risk of cardiovascular hospitalization. Circulation: Arrhythmia and Electrophysiology
Peacock, J., Stanelle, E.J., Johnson, L.C., Hylek, E.M., Kanwar, R., Lakkireddy, D.R., Mittal, S., Passman, R.S., Russo, A.M., Soderlund, D., Hills, M.T., & Piccini, J.P. (2024)
Circulation: Arrhythmia and Electrophysiology
Performance of Atrial Fibrillation Burden Trends for Stroke Risk Stratification
Piccini, J.P., Stanelle, E.J., Johnson, C.C., Hylek, E.M., Kanwar, R., Lakkireddy, D.R., Mittal, S., Peacock, J., Russo, A.M., Soderlund, D., Hills, M.T., & Passman, R.S. (2024)
Journal of Cardiovascular Magnetic Resonance
Non-Invasively Measured Myocardial Torsional Modulus: Comparison to Invasive Evaluation of Diastolic Function
Aufan, M.R., Gupta, H., Sharifov, O.F., Perry, G.J., Denney Jr., T.S., & Lloyd, S.G. (2024)
Journal of Cardiothoracic Surgery
A rare case of IgG4-related aortitis in the thoracic aorta mimicking an intramural hematoma: navigating the diagnostic labyrinth
Alemany, V.S., Fortier, J., Gupta, H., Zaider, A., Grau, J., Burns, P., & Jabagi, H. (2024)
Cardiovascular Pathology
Serotonin transporter deficiency in mice results in an increased susceptibility to HTR2B-dependent pro-fibrotic mechanisms in the cardiac valves and left ventricular myocardium
Castillero, E., Camillo, C., Levine, D., D'Angelo, A.M., Kosuri, Y., Grau, J.B., Levy, R.J., & Ferrari, G. (2024)
PLOS One
Somatostatin receptors in fibrotic myocardium
Castillero, E., Camillo, C., Erwin, W.C., Singh, S., Mohamoud, N., George, I., Eapen, E., Dockery, K., Ferrari, G., & Gupta, H. (2024)
Heart Rhythm
Ineffective cardiac resynchronization pacing is associated with poor outcomes in a nationwide cohort analysis
Robbins-Juarez S.Y., Mittal S., Plummer C., Koehler J.L., Stadler R.W., Ghosh S., Klepfer R.N., & Piccini J.P. (2024)
Heart Rhythm
Prevalence, timing, and impact of early recurrence of atrial tachyarrhythmias after pulsed field ablation: A secondary analysis of the PULSED AF trial
Boersma, L.V.A., Natale, A., Haines, D., DeLurgio, D., Sood, N., Marchlinski, F., Calkins, H., Hoyt, R.H., Sanders, P., Irwin, J., Packer, D., Mittal, S., Durrani, S., DiBiase, L., Sangrigoli, R., Tada, H., Sasano, T., Tomita, H., Yamane, T., … Verma, A. (2024)
European Heart Journal
Prospective deep learning-based quantitative assessment of coronary plaque by ct angiography compared with intravascular ultrasound
Narula, J., Stuckey, T.D., Nakazawa, G., Ahmadi, A., Matsumura, M., Petersen, K., Mirza, S., Ng, N., Mullen, S., Schaap, M., Leipsic, J., Rogers, C., Taylor, C.A., Yacoub, H., Gupta, H., Matsuo, H., Rinehart, S., & Maehara, A. (2024)
Heart Rhythm
Defining the blanking period, using continuous ECG monitoring, after cryoballoon pulmonary vein isolation
Musat, D.L., Milstein, N.S., Saberito, M., Bhatt, A., Habibi, M., Sichrovsky, T.C., Preminger, M.W., Shaw, R.E., & Mittal, S. (2024)
Recent Strategies in High Risk Surgery
Multidimensional frailty instruments for cardiac surgery
Jabagi, H., Haddad, T., Sun, L.Y. (2024)
Heart Rhythm
The potential of artificial intelligence to revolutionize health care delivery, research, and education in cardiac electrophysiology
Al-Khatib, S.M., Singh, J.P., Ghanbari, H., McManus, D.D., Deering, T.F., Avari Silva, J.N., Mittal, S., Krahn, A., & Hurwitz, J.L. (2024)
European Heart Journal
Coronary bypass surgery guided by computed tomography in a low-risk population
Serruys, P.W., Kageyama, S., Pompilio, G., Andreini, D., Pontone, G., Mushtaq, S., La Meir, M., De Mey, J., Tanaka, K., Doenst, T., Teichgräber, U., Schneider, U., Puskas, J.D., Narula, J., Gupta, H., Agarwal, V., Leipsic, J., Masuda, S., Kotoku, N., … Onuma, Y. (2024)
Heart Rhythm
Effects of envelopes on cardiac implantable electronic device pocket healing: A head-to-head preclinical evaluation
Virmani, R., Philippon, F., Mittal, S., Finn, A., Kudlik, D., Kirchhof, N., Lexcen, D., & Kassotis, J. (2024)
JAMA
Pulmonary vein isolation with or without left atrial appendage ligation in atrial fibrillation: The aMAZE randomized clinical trial
Lakkireddy, D.R., Wilber, D.J., Mittal, S., Tschopp, D., Ellis, C.R., Rasekh, A., Hounshell, T., Evonich, R., Chandhok, S., Berger, R.D., Horton, R., Hoskins, M.H., Calkins, H., Yakubov, S.J., Simons, P., Saville, B.R., Lee, R.J., & aMAZE Investigators (2024)
JACC: Clinical Electrophysiology
Mortality benefit among primary prevention implantable cardioverter defibrillator recipients on contemporary heart failure treatment
Ahmed, A., Auricchio, A., Mittal, S., Pickett, R.A., Wilkoff, B.L., Jacobsen, L.D., Marti, A.K., Holbrook, R.W., Soderlund, D.M., & Curtis, A.B. (2024)
Journal of Cardiovascular Electrophysiology
One-year outcomes of pulmonary vein isolation with a novel cryoballoon: Primary results of the FROZEN AF trial
Ellenbogen, K.A., Mittal, S., Varma, N., Aryana, A., Marrouche, N., Anić, A., Nair, D., Champagne, J., Iacopino, S., de Asmundis, C., Weiner, S., Makati, K., Raybuck, J.D., Richards, E., & Su, W. (2024)
Journal of Cardiovascular Computed Tomography
Rationale and design of the CONFIRM2 (Quantitative COroNary CT Angiography Evaluation For Evaluation of Clinical Outcomes: An InteRnational, Multicenter Registry) study
van Rosendael, A.R., Crabtree, T., Bax, J.J., Nakanishi, R., Mushtaq, S., Pontone, G., Andreini, D., Buechel, R.R., Gräni, C., Feuchtner, G., Patel, T.R., Choi, A.D., Al-Mallah, M., Nabi, F., Karlsberg, R.P., Rochitte, C.E., Alasnag, M., Hamdan, A., Cademartiri, F., … Gupta, H., & CONFIRM 2 investigators (2024)
International Journal of Cardiovascular Imaging
Spironolactone improves left atrial function and atrioventricular coupling in patients with resistant hypertension
Girard, A.A., Denney, T.S., Gupta, H., Dell'Italia, L.J., Calhoun, D.A., Oparil, S., Sharifov, O.F., & Lloyd, S.G. (2023)
European Heart Journal Digital Health
Feasibility and accuracy of real-time 3D-holographic graft length measurements
Tsai, T.Y., Kageyama, S., He, X., Pompilio, G., Andreini, D., Pontone, G., La Meir, M., De Mey, J., Tanaka, K., Doenst, T., Puskas, J., Teichgräber, U., Schneider, U., Gupta, H., Leipsic, J., Garg, S., C Revaiah, P., Stanuch, M., Skalski, A.,… Serruys, P.W. (2023)
European Heart Journal Cardiovascular Imaging
Impact of atherosclerosis imaging-quantitative computed tomography on diagnostic certainty, downstream testing, coronary revascularization and medical therapy: The CERTAIN study
Nurmohamed, N.S., Cole, J.H., Budoff, M., Karlsberg, R.P., Gupta, H., Sullenberger, L.E., Quesada, C.G., Rahban, H., Woods, K.M., Uzzilia, J.R., Purga, S.L., Aquino, M., Hoffmann, U., Min, J.K., Earls, J.P., & Choi, A.D. (2024)
The Canadian Journal of Cardiology
Invasive management of hypertrophic cardiomyopathy with clinically important obstruction: Surgical myectomy is superior, but only when accessible
Fortier, J.H., Thapa, Y., Crean, A.M., Gupta, H., & Grau, J.B. (2023)
Heart Rhythm
Expedited loading with intravenous sotalol is safe and feasible - primary results of the prospective evaluation analysis and kinetics of IV sotalol (PEAKS) registry
Steinberg, B.A., Holubkov, R., Deering, T., Groh, C.A., Mittal, S., Kennedy, R., Pokharel, P., Perez, M., Savona, S., Verma, N., Watt, K., Piccini, J.P., & Bunch, T.J. (2024)
European Heart Journal
Tricuspid valve disease and cardiac implantable electronic devices
Andreas, M., Burri, H., Praz, F., Soliman, O., Badano, L., Barreiro, M., Cavalcante, J.L., de Potter, T., Doenst, T., Friedrichs, K., Hausleiter, J., Karam, N., Kodali, S., Latib, A., Marijon, E., Mittal, S., Nickenig, G., Rinaldi, A., Rudzinski, P., … Leclercq, C. (2024)
Reviews in Cardiovascular Medicine
Patient characteristics and outcomes associated with sentinel protection device use in patients with aortic valve disease undergoing TAVR in a “Real-World” setting
Jabagi, H., Shaw, R.E., Gharibeh, L., Tayal, R., Rahim, H., Kim, F., Zapolanski, A., & Grau, J.B. (2024)
American Heart Journal
Comparative effectiveness and healthcare utilization for ambulatory cardiac monitoring strategies in Medicare beneficiaries
Reynolds, M.R., Passman, R., Swindle, J., Mohammadi, I., Wright, B., Boyle, K., Turakhia, M.P., & Mittal, S. (2024)
2023
In H. A. Vohra, L. De Kerchcove, & G. El Khourv (Eds.) El Khoury’s Textbook of Aortic Valve Repair. Nova Medicine Health
Bicuspid Aortic Valve – Anatomy, Echocardiography, and Surgical Techniques
Jabagi, H., & Boodhwani, M.
JACC: Clinical Electrophysiology
Sex-related differences in ventricular tachyarrhythmia events in patients with implantable cardioverter-defibrillator and prior ventricular tachyarrhythmias
Krzowski, B., Kutyifa, V., Vloka, M., Huang, D.T., Attari, M., Aktas, M., Shah, A.H., Musat, D., Rosenthal, L., McNitt, S., Polonsky, B., Schuger, C., Natale, A., Ziv, O., Beck, C., Daubert, J.P., Goldenberg, I., & Zareba, W. (2023)
Cardiovascular Digital Health Journal
Using technology to improve reconnection to remote monitoring in cardiac implantable electronic device patients
Durand, J., Bonnet, J-L. Lazarus, A., Taieb, J., Rosier, A., & Mittal, S. (2023)
Journal of the Society for Cardiovascular Angiography & Interventions
Management of postprocedural conduction disturbances using a prespecified algorithm in the optimize PRO study
Grubb, K.J., Yakubov, S.J., Nazif, T.M., Mittal, S., Gada, H., Fraser, D.G.W., Rovin, J.D., Khalil, R., Pyo, R.T., Sharma, S.K., Ahmed, M., Huang, J., Rodes-Cabau, J. (2023)
Journal of Cardiovascular Computed Tomography
Coronary computed tomography angiography-based SYNTAX score for comprehensive assessment of advanced coronary artery disease
Kageyama, S., Serruys, P.W., Kotoku, N., Garg, S., Ninomiya, K., Masuda, S., Morel, M., Taylor, C.A., Rogers, C., Thomsen, B., Pontone, G., Pompilio, G., Puskas, J.D., Doenst, T., La Meir, M., Teichgräber, U., Gupta, H., De Mey, J., Andreini, D., & Onuma, Y. (2023)
EP Europace
Heliyon
Real-world approach to comprehensive artificial intelligence-aided CT evaluation of coronary artery disease in 530 patients: A retrospective study
Gupta, H., Spanopoulous, B., Lubat, E., Krinsky, G., Rutledge, J., Fortier, J.H., Grau, J.B., & Tayal, R. (2023)
The American Journal of Cardiology
Treatment with microspheres in patients with obstructive hypertrophic cardiomyopathy: An old therapy tries to emerge with long-term outcome data
Musat, D. & Mittal, S. (2023)
HeartRhythm Case Reports
Left atrial appendage closure device embolization - you may not know if you do not look
Musat, D. & Mittal, S. (2023)
Current Treatment Options in Cardiovascular Medicine
Large-bore access and closure: Optimizing vascular access and management of complications
Rahim, H., Rahim, M. & Tayal, R. (2023)
Reviews in Cardiovascular Medicine
Implications of bicuspid aortic valve disease and aortic stenosis/insufficiency as risk factors for thoracic aortic aneurysm
Jabagi, H., Levine, D., Gharibeh, L., Camillo, C., Castillero, E., Ferrari, G., Takayama, H., Grau, J.B. (2023)
International Journal of Cardiology
Coronary artery disease is associated with impaired atrial function regardless of left ventricular filling pressure
Sharifov, O.F., Denney, T.S., Jr, Girard, A.A., Gupta, H., & Lloyd, S.G. (2023)
Circulation: Cardiovascular Interventions
Transcatheter aortic valve replacement and impact of subclinical leaflet thrombosis in low-risk patients: LRT trial 4-year outcomes
"Waksman, R., Bhogal, S., Gordon, P., Ehsan, A., Wilson, S.R., Levitt, R., Parikh, P., Bilfinger, T., Hanna, N., Buchbinder, M., Asch, F.M., Kim, F.Y., Weissman, G., Ben-Dor, I., Shults, C.C., Ali, S., Sutton, J.A., Shea, C., Zhang, C., Garcia-Garcia, H.M., … Rogers, T. (2023)
Heart Rhythm
2023 HRS/EHRA/APHRS/LAHRS expert consensus statement on practical management of the remote device clinic
Ferrick, A.M., Raj, S.R., Deneke, T., Kojodjojo, P., Lopez-Cabanillas, N., Abe, H., Boveda, S., Chew, D.S., Choi, J.I., Dagres, N., Dalal, A.S., Dechert, B.E., Frazier-Mills, C.G., Gilbert, O., Han, J.K., Hewit, S., Kneeland, C., Mirza, S.D., Mittal, S.,…Varma, N. (2023)
European Journal of Cardio-Thoracic Surgery
Patients with hypertrophic cardiomyopathy deserve heart teams, and those heart teams need surgeons
Grau, J.B., & Fortier, J.H. (2023).
Trends in Cardiovascular Medicine
Transcatheter aortic valve implantation versus surgical aortic valve replacement in chronic kidney disease: Meta-analysis of reconstructed time-to-event data
Jacquemyn, X., Van den Eynde, J., Iwens, Q., Billiau, J., Jabagi, H., Serna-Gallegos, D., Chu, D., Sultan, I., & Sá, M.P. (2023).
Circulation: Arrhythmia and Electrophysiology
Randomized trial of stand-alone use of the antimicrobial envelope in high-risk cardiac device patients
Ellis, C.R., Greenspon, A.J., Andriulli, J.A., Gould, P.A., Carillo, R., Kolek, M.J., Donegan, R., Amaral, A.P., & Mittal, S. (2023).
Heart Rhythm
Early mortality after inpatient versus outpatient catheter ablation in patients with atrial fibrillation
Obeid, M. J., Zhou, J., Sale, A. J., Longacre, C., Zeitler, E. P., Andrade, J., Mittal, S., & Piccini, J. P. (2023).
Circulation: Arrhythmia and electrophysiology
Advances in cardiac electrophysiology
Piccini, J. P., Russo, A. M., Sharma, P. S., Kron, J., Tzou, W., Sauer, W., Park, D. S., Birgersdotter-Green, U., Frankel, D. S., Healey, J. S., Hummel, J., Koruth, J., Linz, D., Mittal, S., Nair, D. G., Nattel, S., Noseworthy, P. A., Steinberg, B. A., Trayanova, N. A., Wan, E. Y., … Wang, P. J. (2022).
JACC: Cardiovascular Interventions
Clinical impact of standardized TAVR technique and care pathway
Grubb, K. J., Gada, H., Mittal, S., Nazif, T., Rodés-Cabau, J., Fraser, D. G. W., Lin, L., Rovin, J. D., Khalil, R., Sultan, I., Gardner, B., Lorenz, D., Chetcuti, S. J., Patel, N. C., Harvey, J. E., Mahoney, P., Schwartz, B., Jafar, Z., Wang, J., … Yakubov, S. J. (2023).
Science Translational Medicine
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation
Castillero, E., Fitzpatrick, E., Keeney, S. J., D'Angelo, A. M., Pressly, B. B., Simpson, M. T., Kurade, M., Erwin, W. C., Moreno, V., Camillo, C., Shukla, H. J., Inamdar, V. V., Aghali, A., Grau, J. B., Salvati, E., Nissim, I., Rauova, L., Oyama, M. A., Stachelek, S. J., … Ferrari, G. (2023, January).