FACTORS ASSOCIATED WITH RESPONSE TO CARDIAC RESYNCHRONIZATION THERAPY IN HEART FAILURE PATIENTS WITH NON-LBBB ECG PATTERN
Objective
This study is being conducted prospectively validate previously identified predictors of echocardiography response to CRT-D in HF patients with non-LBBB, and identify novel ECG variables and echocardiography variables to predict response. The study will investigate whether these variables predict clinical outcomes in this cohort.
Eligibility
- Age 18 years or older (no upper limit)
- Optimal medical therapy for heart failure as established by current guidelines
- Class IIa or IIb guideline-based indication for CRT-D in non-LBBB patients, including one of the following:
- New York Heart Association (NYHA) class II HF symptoms,LVEF ≤ 30% and QRS≥ 150 ms (IIb)
- NYHA class III-IVa HF, LVEF ≤ 35%, and QRS duration ≥ 150 ms (IIa)
- NYHA class III-IVa HF, LVEF ≤ 35%, and QRS duration 120-149 ms (IIb)
- Successful CRT-D generator implant
