Prospective Randomized Trial of the Optimal Evaluation of Cardiac Symptoms and Revascularization
The study will be a prospective, pragmatic, randomized clinical trial of the comparative effectiveness of diagnostic evaluation strategies for stable CAD, to be performed in outpatient settings, including primary care and cardiology practices.
- Stable typical or atypical symptoms suggesting possible coronary artery disease (CAD) with further non-emergent testing or elective catheterization recommended to evaluate the presence of suspected CAD
- Safe performance of cCTA:
- Creatinine clearance ≥45 ml/min
- For a female participant of childbearing potential, a pregnancy test must be performed with negative results known within 7 days prior to randomization
- Willingness to comply with all aspects of the protocol, including adherence to the assigned strategy and follow-up visits